Keywords

Amyloidosis; Aortic Valve Stenosis; Fibrosis; Heart Failure, Diastolic; Mitral Valve Insufficiency; Multimodal Imaging; Prognosis; Tricuspid Valve Insufficiency

Research interests

My working group at present mainly focuses on valvular heart disease and trans-catheter valve interventions. We are investigating new predictors of outcome following TAVR as well as edge-to-edge mitral and tricuspid valve repair. We furthermore use multimodality imaging and particularly cardiac magnetic resonance imaging to non-invasively study alterations of the myocardial structure caused by pathological conditions including valvular heart disease, heart failure with an emphasis on heart failure with preserved ejection fraction (HFPEF), and cardiac amyloidosis. 

Selected publications

1. Nitsche C, Aschauer S, Kammerlander AA, Schneider M, Poschner T, Duca F, Binder C, Koschutnik M, Stiftinger J, Goliasch G, Siller-Matula J, Winter MP, Anvari-Pirsch A, Andreas M, Geppert A, Beitzke D, Loewe C, Hacker M, Agis H, Kain R, Lang I, Bonderman D, Hengstenberg C, Mascherbauer J. Light-chain and transthyretin cardiac amyloidosis in severe aortic stenosis: prevalence, screening possibilities, and outcome. Eur J Heart Fail. 2020 Feb 20. doi: 10.1002/ejhf.1756.
2. Nitsche C, Kammerlander AA, Knechtelsdorfer K, Kraiger JA, Goliasch G, Dona C, Schachner L, Öztürk B, Binder C, Duca F, Aschauer S, Zimpfer D, Bonderman D, Hengstenberg C, Mascherbauer J. Determinants of Bioprosthetic Aortic Valve Degeneration. JACC Cardiovasc Imaging. 2020 Feb;13(2 Pt 1):345-353. doi: 10.1016/j.jcmg.2019.01.027.
3. Bartko PE, Clavel MA, Annabi MS, Dahou A, Ristl R, Goliasch G, Baumgartner H, Hengstenberg C, Cavalcante JL, Burwash I, Enriquez-Sarano M, Bergler-Klein J, Rodés-Cabau J, Pibarot P, Mascherbauer J. Sex-Related Differences in Low-Gradient, Low-Ejection Fraction Aortic Stenosis: Results From the Multicenter TOPAS Study. JACC Cardiovasc Imaging. 2019 Jan;12(1):203-205. doi: 10.1016/j.jcmg.2018.11.003.
4. Goliasch G, Kammerlander AA, Nitsche C, Dona C, Schachner L, Öztürk B, Binder C, Duca F, Aschauer S, Laufer G, Hengstenberg C, Bonderman D, Mascherbauer J. Syncope: The Underestimated Threat in Severe Aortic Stenosis. JACC Cardiovasc Imaging. 2019 Feb;12(2):225-232. doi: 10.1016/j.jcmg.2018.09.020.
5. Kammerlander AA, Wiesinger M, Duca F, Aschauer S, Binder C, Zotter Tufaro C, Nitsche C, Badre-Eslam R, Schönbauer R, Bartko P, Beitzke D, Loewe C, Hengstenberg C, Bonderman D, Mascherbauer J. Diagnostic and Prognostic Utility of Cardiac Magnetic Resonance Imaging in Aortic Regurgitation. JACC Cardiovasc Imaging. 2019 Aug;12(8 Pt 1):1474-1483. doi: 10.1016/j.jcmg.2018.08.036.